Assay Detail
Binding
CHEMBL1785601
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Displacement of fluorescent 1-anilinonapthalene 8-sulfonic acid from human h-FABP by fluorescence spectrophotometry
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
New aromatic substituted pyrazoles as selective inhibitors of human adipocyte fatty acid-binding protein.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 8 | 5.33 | 5.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1782967 | — | — | 1 | 5.64 |
| CHEMBL247920 | — | — | 1 | 5.46 |
| CHEMBL1782968 | — | — | 1 | 5.43 |
| CHEMBL1782965 | — | — | 1 | 5.38 |
| CHEMBL1782966 | — | — | 1 | 5.37 |
| CHEMBL1782963 | — | — | 1 | 5.28 |
| CHEMBL1782964 | — | — | 1 | 4.77 |
| CHEMBL1782969 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1782967 | — | Ki | = | 2270.0 | nM | 5.64 |
| CHEMBL247920 | — | Ki | = | 3470.0 | nM | 5.46 |
| CHEMBL1782968 | — | Ki | = | 3720.0 | nM | 5.43 |
| CHEMBL1782965 | — | Ki | = | 4130.0 | nM | 5.38 |
| CHEMBL1782966 | — | Ki | = | 4240.0 | nM | 5.37 |
| CHEMBL1782963 | — | Ki | = | 5240.0 | nM | 5.28 |
| CHEMBL1782964 | — | Ki | = | 17000.0 | nM | 4.77 |
| CHEMBL1782969 | — | Ki | > | 50000.0 | nM | - |