Assay Detail
Binding
CHEMBL1785682
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of mouse alpha6alpha4beta3beta2 nAChR
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Target
Neuronal acetylcholine receptor subunit alpha-6/beta-2 (CHEMBL3885611) ↗| Type | PROTEIN COMPLEX |
| Organism | Mus musculus |
Publication
Evaluation of structurally diverse neuronal nicotinic receptor ligands for selectivity at the alpha6( *) subtype.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 5.84 | 6.07 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1783881 | — | — | 1 | 6.07 |
| CHEMBL1783882 | — | — | 1 | 5.60 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1783881 | — | Ki | = | 850.0 | nM | 6.07 |
| CHEMBL1783882 | — | Ki | = | 2500.0 | nM | 5.60 |