Assay Detail
Binding
CHEMBL1786487
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Binding affinity to HSP70 by surface plasmon resonance analysis
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Adenosine-derived inhibitors of 78 kDa glucose regulated protein (Grp78) ATPase: insights into isoform selectivity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 4 | 6.27 | 7.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL462871 | — | — | 1 | 7.30 |
| CHEMBL470334 | — | — | 1 | 6.52 |
| CHEMBL14830 | ADENOSINE DIPHOSPHATE | 0.5 | 1 | 6.30 |
| CHEMBL516197 | — | — | 1 | 4.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL462871 | — | Kd | = | 50.0 | nM | 7.30 |
| CHEMBL470334 | — | Kd | = | 300.0 | nM | 6.52 |
| CHEMBL14830 | ADENOSINE DIPHOSPHATE | Kd | = | 500.0 | nM | 6.30 |
| CHEMBL516197 | — | Kd | = | 11000.0 | nM | 4.96 |