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Assay Detail

CHEMBL1786816

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of chicken myosin 5a assessed as ATP hydrolysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Gallus gallus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Unconventional myosin-Va (CHEMBL1781866)
Type SINGLE PROTEIN
Organism Gallus gallus

Publication

Inhibition of Myosin ATPase activity by halogenated pseudilins: a structure-activity study.
Preller M, Chinthalapudi K, Martin R, Knolker HJ, Manstein DJ.
J Med Chem (2011) 54 : 3675 -3685
PubMed 21534527 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.92 5.92

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1235156 PENTABROMOPSEUDILIN 1 5.92

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1235156 PENTABROMOPSEUDILIN IC50 = 1200.0 nM 5.92