Assay Detail
Binding
CHEMBL1798142
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Binding affinity to adrenergic Alpha-1D receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Novel 4-phenylpiperidine-2,6-dione derivatives. Ligands for α₁-adrenoceptor subtypes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 9.21 | 9.44 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL301707 | — | — | 1 | 9.44 |
| CHEMBL543741 | — | — | 1 | 8.98 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL301707 | — | Ki | = | 0.3631 | nM | 9.44 |
| CHEMBL543741 | — | Ki | = | 1.047 | nM | 8.98 |