Assay Detail
Binding
CHEMBL1798568
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Binding affinity to JMJD2E
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Inhibitors of histone demethylases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.29 | 5.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL600221 | — | — | 1 | 5.30 |
| CHEMBL602502 | — | — | 1 | 5.30 |
| CHEMBL602503 | — | — | 1 | 5.27 |
| CHEMBL1797656 | — | — | 1 | - |
| CHEMBL1797657 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL600221 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL602502 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL602503 | — | IC50 | = | 5400.0 | nM | 5.27 |
| CHEMBL1797656 | — | IC50 | = | 200000.0 | nM | - |
| CHEMBL1797657 | — | IC50 | = | 200000.0 | nM | - |