Assay Detail
Binding
CHEMBL1799268
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]-DPDPE from DOR-1 expressed in CHO cells after 60 mins
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | CHO |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Generation of novel radiolabeled opiates through site-selective iodination.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 8.33 | 9.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1795711 | — | — | 1 | 9.24 |
| CHEMBL1795712 | — | — | 1 | 8.59 |
| CHEMBL1795713 | — | — | 1 | 7.15 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1795711 | — | Ki | = | 0.58 | nM | 9.24 |
| CHEMBL1795712 | — | Ki | = | 2.55 | nM | 8.59 |
| CHEMBL1795713 | — | Ki | = | 70.76 | nM | 7.15 |