Assay Detail
Functional
CHEMBL1803191
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Cytotoxicity against human vincristine-resistant U937 cells after 72 hrs by fluorometric microculture cytotoxicity assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | U-937 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Isolation, sequencing, and structure-activity relationships of cyclotides.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.03 | 6.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL525223 | CYCLOVIOLACIN O2 | — | 1 | 6.96 |
| CHEMBL1801035 | — | — | 1 | 5.58 |
| CHEMBL1801140 | — | — | 1 | 5.56 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL525223 | CYCLOVIOLACIN O2 | IC50 | = | 110.0 | nM | 6.96 |
| CHEMBL1801035 | — | IC50 | = | 2630.0 | nM | 5.58 |
| CHEMBL1801140 | — | IC50 | = | 2730.0 | nM | 5.56 |