Assay Detail
Binding
CHEMBL1803932
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [125I]IMPY from amyloid beta (1-42) after 2 hrs by gamma counting
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Novel quinoxaline derivatives for in vivo imaging of β-amyloid plaques in the brain.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 8.34 | 8.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1800535 | — | — | 1 | 8.80 |
| CHEMBL1800536 | — | — | 1 | 8.59 |
| CHEMBL1800080 | — | — | 1 | 8.52 |
| CHEMBL1800537 | — | — | 1 | 8.39 |
| CHEMBL1800539 | — | — | 1 | 8.11 |
| CHEMBL78012 | — | — | 1 | 7.98 |
| CHEMBL1800538 | — | — | 1 | 7.97 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1800535 | — | Ki | = | 1.6 | nM | 8.80 |
| CHEMBL1800536 | — | Ki | = | 2.6 | nM | 8.59 |
| CHEMBL1800080 | — | Ki | = | 3.0 | nM | 8.52 |
| CHEMBL1800537 | — | Ki | = | 4.1 | nM | 8.39 |
| CHEMBL1800539 | — | Ki | = | 7.7 | nM | 8.11 |
| CHEMBL78012 | — | Ki | = | 10.5 | nM | 7.98 |
| CHEMBL1800538 | — | Ki | = | 10.7 | nM | 7.97 |