Assay Detail
Binding
CHEMBL1805281
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Binding affinity to eEF1A2 expressed in human MDA-MB-231 cells using 1 uM biotinylated compound immobilized on streptavidin sensor chip by surface plasmon resonance method
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | MDA-MB-231 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Novel flavonoids with antiproliferative activities against breast cancer cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 8.42 | 8.61 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1802815 | — | — | 1 | 8.61 |
| CHEMBL1802973 | — | — | 1 | 8.34 |
| CHEMBL1802814 | — | — | 1 | 8.31 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1802815 | — | Kd | = | 2.43 | nM | 8.61 |
| CHEMBL1802973 | — | Kd | = | 4.54 | nM | 8.34 |
| CHEMBL1802814 | — | Kd | = | 4.89 | nM | 8.31 |