Assay Detail
Functional
CHEMBL1805851
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at mineralocorticoid receptor in human A549 cells
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A549 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Dimethyl-diphenyl-propanamide derivatives as nonsteroidal dissociated glucocorticoid receptor agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 7 | 8.70 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL131 | PREDNISOLONE | 4.0 | 1 | 8.70 |
| CHEMBL1801012 | — | — | 1 | - |
| CHEMBL1801008 | — | — | 1 | - |
| CHEMBL1801006 | — | — | 1 | - |
| CHEMBL1800981 | — | — | 1 | - |
| CHEMBL1800984 | — | — | 1 | - |
| CHEMBL1800985 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL131 | PREDNISOLONE | EC50 | = | 2.0 | nM | 8.70 |
| CHEMBL1801012 | — | EC50 | > | 5000.0 | nM | - |
| CHEMBL1801008 | — | EC50 | > | 5000.0 | nM | - |
| CHEMBL1801006 | — | EC50 | > | 5000.0 | nM | - |
| CHEMBL1800981 | — | EC50 | > | 5000.0 | nM | - |
| CHEMBL1800984 | — | EC50 | > | 5000.0 | nM | - |
| CHEMBL1800985 | — | EC50 | > | 5000.0 | nM | - |