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Assay Detail

CHEMBL1809982

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human SW480 cells after 72 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type SW480
Confidence 1 — Organism
Curated By Autocuration

Target

SW480 (CHEMBL612544)
Type CELL-LINE
Organism Homo sapiens

Publication

Synthesis and biological evaluation of 4-nitro-substituted 1,3-diaryltriazenes as a novel class of potent antitumor agents.
Cimbora-Zovko T, Brozovic A, Piantanida I, Fritz G, Virag A, Alič B, Majce V, Kočevar M, Polanc S, Osmak M.
Eur J Med Chem (2011) 46 : 2971 -2983
PubMed 21550697 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.28 6.28

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1807120 1 6.28

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1807120 IC50 = 530.0 nM 6.28