Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL1816043

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to human arginase 1
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Arginase-1 (CHEMBL1075097)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Binding of α,α-disubstituted amino acids to arginase suggests new avenues for inhibitor design.
Ilies M, Di Costanzo L, Dowling DP, Thorn KJ, Christianson DW.
J Med Chem (2011) 54 : 5432 -5443
PubMed 21728378 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 8.30 8.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1812661 1 8.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1812661 Kd = 5.0 nM 8.30