Assay Detail
Binding
CHEMBL1816873
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant PIM1 assessed as 33Pi incorporation after 60 mins by scintillation counting
4
Total Activities
4
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Serine/threonine-protein kinase pim-1 (CHEMBL2147) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Arthrinins A-D: novel diterpenoids and further constituents from the sponge derived fungus Arthrinium sp.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Inhibition | 2 | - | - |
| IC50 | 2 | 6.52 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL466154 | NORLICHEXANTHONE | — | 1 | 6.52 |
| CHEMBL454440 | ANOMALIN A | — | 1 | 6.52 |
| CHEMBL1812030 | MYROCIN D | — | 1 | - |
| CHEMBL516554 | MYROCIN A | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL466154 | NORLICHEXANTHONE | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL454440 | ANOMALIN A | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL1812030 | MYROCIN D | Inhibition | - | % | - | |
| CHEMBL516554 | MYROCIN A | Inhibition | - | % | - |