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Assay Detail

CHEMBL1819975

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of AurA expressed in Escherichia coli or baculovirus-infected insect cells by IMAP assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Aurora kinase A (CHEMBL4722)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Selectivity of kinase inhibitor fragments.
Bamborough P, Brown MJ, Christopher JA, Chung CW, Mellor GW.
J Med Chem (2011) 54 : 5131 -5143
PubMed 21699136 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.70 7.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL522476 1 7.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL522476 IC50 = 20.0 nM 7.70