Assay Detail
Binding
CHEMBL1820951
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Modulation of HIF1 expressed in HEK293 cells assessed as luciferase activity under hypoxic condition after 24 hrs by luminometer analysis
4
Total Activities
4
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | HEK293 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Isolation, identification, and biological evaluation of HIF-1-modulating compounds from Brazilian green propolis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Activity | 2 | - | - |
| IC50 | 2 | 4.35 | 4.59 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL464997 | DRUPANIN | — | 1 | 4.59 |
| CHEMBL511708 | BACCHARIN | — | 1 | 4.11 |
| CHEMBL311155 | BETULETOL | — | 1 | - |
| CHEMBL470266 | ISOSAKUTANETIN | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL464997 | DRUPANIN | IC50 | = | 25600.0 | nM | 4.59 |
| CHEMBL511708 | BACCHARIN | IC50 | = | 77400.0 | nM | 4.11 |
| CHEMBL311155 | BETULETOL | Activity | - | — | - | |
| CHEMBL470266 | ISOSAKUTANETIN | Activity | - | — | - |