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Assay Detail

CHEMBL1825337

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Agonist activity at human TRPv1 receptor expressed in HEK293 cells assessed as stimulation of intracellular calcium level using Fluo4-AM dye based fluorimetric assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HEK293
Confidence 9 — Direct single protein target
Curated By Autocuration

Publication

Bioactive prenylogous cannabinoid from fiber hemp (Cannabis sativa).
Pollastro F, Taglialatela-Scafati O, Allarà M, Muñoz E, Di Marzo V, De Petrocellis L, Appendino G.
J Nat Prod (2011) 74 : 2019 -2022
PubMed 21902175 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 2 5.63 5.89

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL497318 CANNABIGEROL 2.0 1 5.89
CHEMBL1823117 SESQUICANNABIGEROL 1 5.36

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL497318 CANNABIGEROL EC50 = 1300.0 nM 5.89
CHEMBL1823117 SESQUICANNABIGEROL EC50 = 4400.0 nM 5.36