Assay Detail
Functional
CHEMBL1825489
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Antiproliferative activity against human A549 cells assessed as loss of cell viability after 48 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A549 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Curcumin recognizes a unique binding site of tubulin.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.97 | 5.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL428441 | — | — | 1 | 5.16 |
| CHEMBL140 | CURCUMIN | 3.0 | 1 | 4.77 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL428441 | — | IC50 | = | 7000.0 | nM | 5.16 |
| CHEMBL140 | CURCUMIN | IC50 | = | 17000.0 | nM | 4.77 |