Assay Detail
Binding
CHEMBL1825635
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of TNF-alpha-induced Nuclear factor-kappa-B-mediated ICAM-1 expression in human HMEC1 cells after 24 hrs by FACS analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HMEC1 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
The selective P-TEFb inhibitor CAN508 targets angiogenesis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 4.70 | 4.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL215205 | — | — | 1 | 4.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL215205 | — | IC50 | = | 20000.0 | nM | 4.70 |