Assay Detail
Binding
CHEMBL1827781
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Induction of quorum sensing activity in Pseudomonas aeruginosa assessed as maximal induction of LasR-dependent yellow fluorescent protein emission by luminescence assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Pseudomonas aeruginosa |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Medicinal chemistry as a conduit for the modulation of quorum sensing.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 6.84 | 7.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1236450 | — | — | 1 | 7.85 |
| CHEMBL1823944 | — | — | 1 | 6.62 |
| CHEMBL1236463 | — | — | 1 | 6.04 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1236450 | — | EC50 | = | 14.0 | nM | 7.85 |
| CHEMBL1823944 | — | EC50 | = | 240.0 | nM | 6.62 |
| CHEMBL1236463 | — | EC50 | = | 920.0 | nM | 6.04 |