Assay Detail
Binding
CHEMBL1827782
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Inhibition of quorum sensing in Pseudomonas aeruginosa assessed as inhibition of LasR-dependent yellow fluorescent protein emission by luminescence assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Pseudomonas aeruginosa |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Medicinal chemistry as a conduit for the modulation of quorum sensing.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.61 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1818523 | — | — | 1 | 7.52 |
| CHEMBL1823942 | — | — | 1 | 5.00 |
| CHEMBL1823945 | — | — | 1 | 4.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1818523 | — | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL1823942 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL1823945 | — | IC50 | = | 50000.0 | nM | 4.30 |