Assay Detail
Binding
CHEMBL1827928
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Inhibition of quorum sensing Salmonella Typhimurium by beta-galactosidase transcription assay in presence of 50 uM DPD
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Salmonella enterica subsp. enterica serovar Typhimurium |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Medicinal chemistry as a conduit for the modulation of quorum sensing.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.97 | 5.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL539143 | — | — | 1 | 5.30 |
| CHEMBL539221 | — | — | 1 | 5.28 |
| CHEMBL1824157 | — | — | 1 | 4.69 |
| CHEMBL550518 | — | — | 1 | 4.60 |
| CHEMBL1824156 | — | — | 1 | - |
| CHEMBL560745 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL539143 | — | IC50 | = | 5040.0 | nM | 5.30 |
| CHEMBL539221 | — | IC50 | = | 5300.0 | nM | 5.28 |
| CHEMBL1824157 | — | IC50 | = | 20300.0 | nM | 4.69 |
| CHEMBL550518 | — | IC50 | = | 24900.0 | nM | 4.60 |
| CHEMBL1824156 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL560745 | — | IC50 | > | 50000.0 | nM | - |