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Assay Detail

CHEMBL1831550

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of CDK5
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Cyclin-dependent kinase 5 (CHEMBL4036)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

CNS and antimalarial activity of synthetic meridianin and psammopemmin analogs.
Lebar MD, Hahn KN, Mutka T, Maignan P, McClintock JB, Amsler CD, van Olphen A, Kyle DE, Baker BJ.
Bioorg Med Chem (2011) 19 : 5756 -5762
PubMed 21907583 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.46 5.46

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL50498 MERIDIANIN A 1 5.46

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL50498 MERIDIANIN A IC50 = 3500.0 nM 5.46