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Assay Detail

CHEMBL1833373

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of [3H]YM-09151-2 from human D2 receptor expressed in CHO cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type CHO
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

D(2) dopamine receptor (CHEMBL217)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Synthesis and pharmacological evaluation of indole-based sigma receptor ligands.
Mésangeau C, Amata E, Alsharif W, Seminerio MJ, Robson MJ, Matsumoto RR, Poupaert JH, McCurdy CR.
Eur J Med Chem (2011) 46 : 5154 -5161
PubMed 21899931 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.06 6.06

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1831166 1 6.06

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1831166 Ki = 870.0 nM 6.06