Assay Detail
Binding
CHEMBL1837252
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of bovine tubulin assembly after 1 hr by fluorescence assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Design and synthesis of resveratrol-based nitrovinylstilbenes as antimitotic agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.37 | 5.71 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL107 | COLCHICINE | 4.0 | 1 | 5.71 |
| CHEMBL1836543 | — | — | 1 | 5.37 |
| CHEMBL1836545 | — | — | 1 | 5.31 |
| CHEMBL1836547 | — | — | 1 | 5.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL107 | COLCHICINE | IC50 | = | 1960.0 | nM | 5.71 |
| CHEMBL1836543 | — | IC50 | = | 4270.0 | nM | 5.37 |
| CHEMBL1836545 | — | IC50 | = | 4900.0 | nM | 5.31 |
| CHEMBL1836547 | — | IC50 | = | 8020.0 | nM | 5.10 |