Assay Detail
Binding
CHEMBL1837629
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Displacement of [3H]-CP-55,940 from human CB1 receptor expressed in human HEK293 cells after 90 mins by radioligand assay
7
Total Activities
4
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Homology modeling in tandem with 3D-QSAR analyses: a computational approach to depict the agonist binding site of the human CB2 receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 7.21 | 7.21 |
| IC50 | 3 | 6.81 | 6.81 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1836189 | — | — | 2 | 7.21 |
| CHEMBL1836188 | — | — | 2 | - |
| CHEMBL1836121 | — | — | 2 | - |
| CHEMBL1836187 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1836189 | — | Ki | = | 62.0 | nM | 7.21 |
| CHEMBL1836189 | — | IC50 | = | 155.0 | nM | 6.81 |
| CHEMBL1836188 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL1836121 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL1836187 | — | Ki | = | 163400.0 | nM | - |
| CHEMBL1836188 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL1836121 | — | Ki | > | 10000.0 | nM | - |