Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL1839747

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human recombinant MMP3 assessed as hydrolysis of MOCAcPLGLA2pr(Dnp)AR-NH2 by fluorescence spectrofluorometry
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Stromelysin-1 (CHEMBL283)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Selective water-soluble gelatinase inhibitor prodrugs.
Gooyit M, Lee M, Schroeder VA, Ikejiri M, Suckow MA, Mobashery S, Chang M.
J Med Chem (2011) 54 : 6676 -6690
PubMed 21866961 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 4.91 4.91

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL485492 1 4.91

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL485492 Ki = 12200.0 nM 4.91