Assay Detail
Binding
CHEMBL1839795
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of FITC-labeled fibrinogen from alpha2beta3 in human platelets
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Publication
RGD mimetics containing phthalimidine fragment as novel ligands of fibrinogen receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 7.17 | 8.26 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1836344 | — | — | 1 | 8.26 |
| CHEMBL1836347 | — | — | 1 | 8.19 |
| CHEMBL1836351 | — | — | 1 | 8.19 |
| CHEMBL1836345 | — | — | 1 | 8.17 |
| CHEMBL1836355 | — | — | 1 | 7.66 |
| CHEMBL1836350 | — | — | 1 | 7.43 |
| CHEMBL1836342 | — | — | 1 | 6.57 |
| CHEMBL1836348 | — | — | 1 | 6.46 |
| CHEMBL1836343 | — | — | 1 | 5.92 |
| CHEMBL265628 | — | — | 1 | 4.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1836344 | — | IC50 | = | 5.5 | nM | 8.26 |
| CHEMBL1836347 | — | IC50 | = | 6.5 | nM | 8.19 |
| CHEMBL1836351 | — | IC50 | = | 6.5 | nM | 8.19 |
| CHEMBL1836345 | — | IC50 | = | 6.8 | nM | 8.17 |
| CHEMBL1836355 | — | IC50 | = | 22.0 | nM | 7.66 |
| CHEMBL1836350 | — | IC50 | = | 37.0 | nM | 7.43 |
| CHEMBL1836342 | — | IC50 | = | 270.0 | nM | 6.57 |
| CHEMBL1836348 | — | IC50 | = | 350.0 | nM | 6.46 |
| CHEMBL1836343 | — | IC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL265628 | — | IC50 | = | 13000.0 | nM | 4.89 |