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Assay Detail

CHEMBL1912153

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antibiofilm activity against Paracoccus sp. 4M6 assessed as inhibition of bacterial adhesion after 15 hrs by fluorescence assay
22
Total Activities
22
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Paracoccus sp.
Confidence 1 — Organism
Curated By Autocuration

Target

Paracoccus sp. (CHEMBL4513215)
Type ORGANISM
Organism Paracoccus sp.

Publication

Designing 2-aminoimidazole alkaloids analogs with anti-biofilm activities: structure-activities relationships of polysubstituted triazoles.
Linares D, Bottzeck O, Pereira O, Praud-Tabariès A, Blache Y.
Bioorg Med Chem Lett (2011) 21 : 6751 -6755
PubMed 21982498 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 22 4.21 4.38

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1910932 1 4.38
CHEMBL1910926 1 4.04
CHEMBL1910823 1 -
CHEMBL1910824 1 -
CHEMBL1910825 1 -
CHEMBL1910826 1 -
CHEMBL1910827 1 -
CHEMBL1910923 1 -
CHEMBL1910924 1 -
CHEMBL1910925 1 -
CHEMBL1514247 1 -
CHEMBL1910822 1 -
CHEMBL1910928 1 -
CHEMBL1910921 1 -
CHEMBL1910922 1 -
CHEMBL1910929 1 -
CHEMBL1910930 1 -
CHEMBL1910931 1 -
CHEMBL1910933 1 -
CHEMBL1910934 1 -
CHEMBL1910935 1 -
CHEMBL1910927 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1910932 EC50 = 41200.0 nM 4.38
CHEMBL1910926 EC50 = 90300.0 nM 4.04
CHEMBL1910823 EC50 > 200000.0 nM -
CHEMBL1910824 EC50 > 200000.0 nM -
CHEMBL1910825 EC50 = 199300.0 nM -
CHEMBL1910826 EC50 > 200000.0 nM -
CHEMBL1910827 EC50 > 200000.0 nM -
CHEMBL1910923 EC50 > 200000.0 nM -
CHEMBL1910924 EC50 > 200000.0 nM -
CHEMBL1910925 EC50 > 200000.0 nM -
CHEMBL1514247 EC50 > 200000.0 nM -
CHEMBL1910822 EC50 > 200000.0 nM -
CHEMBL1910928 EC50 > 200000.0 nM -
CHEMBL1910921 EC50 = 199300.0 nM -
CHEMBL1910922 EC50 > 200000.0 nM -
CHEMBL1910929 EC50 > 200000.0 nM -
CHEMBL1910930 EC50 > 200000.0 nM -
CHEMBL1910931 EC50 > 200000.0 nM -
CHEMBL1910933 EC50 > 200000.0 nM -
CHEMBL1910934 EC50 = 130800.0 nM -
CHEMBL1910935 EC50 = 181100.0 nM -
CHEMBL1910927 EC50 > 200000.0 nM -