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Assay Detail

CHEMBL1912415

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of CDK1
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Cyclin-dependent kinase 1 (CHEMBL308)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

A modular approach to trim cellular targets in anticancer drug discovery.
Ríos-Luci C, Domínguez-Kelly R, León LG, Díaz-Rodríguez E, Freire R, Pandiella A, Cikotiene I, Padrón JM.
Bioorg Med Chem Lett (2011) 21 : 6641 -6645
PubMed 21986585 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 5.60 5.60

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL303958 1 5.60

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL303958 Ki = 2500.0 nM 5.60