Assay Detail
Binding
CHEMBL1918238
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of aromatase after 10 mins preincubation by plate reader relative to control
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Design, synthesis, and biological evaluation of callophycin A and analogues as potential chemopreventive and anticancer agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 4.55 | 6.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL9352 | NARINGENIN | — | 1 | 6.64 |
| CHEMBL1915403 | — | — | 1 | 4.98 |
| CHEMBL1915151 | — | — | 1 | 4.35 |
| CHEMBL1915167 | — | — | 1 | 4.33 |
| CHEMBL1915401 | — | — | 1 | 4.24 |
| CHEMBL1915161 | — | — | 1 | 4.23 |
| CHEMBL1915156 | — | — | 1 | 4.20 |
| CHEMBL1915152 | — | — | 1 | 4.19 |
| CHEMBL1915159 | — | — | 1 | 4.17 |
| CHEMBL1915176 | — | — | 1 | 4.14 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL9352 | NARINGENIN | IC50 | = | 230.0 | nM | 6.64 |
| CHEMBL1915403 | — | IC50 | = | 10500.0 | nM | 4.98 |
| CHEMBL1915151 | — | IC50 | = | 44800.0 | nM | 4.35 |
| CHEMBL1915167 | — | IC50 | = | 47300.0 | nM | 4.33 |
| CHEMBL1915401 | — | IC50 | = | 57400.0 | nM | 4.24 |
| CHEMBL1915161 | — | IC50 | = | 58600.0 | nM | 4.23 |
| CHEMBL1915156 | — | IC50 | = | 63200.0 | nM | 4.20 |
| CHEMBL1915152 | — | IC50 | = | 64500.0 | nM | 4.19 |
| CHEMBL1915159 | — | IC50 | = | 68100.0 | nM | 4.17 |
| CHEMBL1915176 | — | IC50 | = | 72000.0 | nM | 4.14 |