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Assay Detail

CHEMBL1921608

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of IMPDH2
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Inosine-5'-monophosphate dehydrogenase 2 (CHEMBL2002)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Aminothiazoles as γ-secretase modulators.
Lübbers T, Flohr A, Jolidon S, David-Pierson P, Jacobsen H, Ozmen L, Baumann K.
Bioorg Med Chem Lett (2011) 21 : 6554 -6558
PubMed 21924610 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.40 6.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1915558 1 6.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1915558 IC50 = 400.0 nM 6.40