Assay Detail
Binding
CHEMBL1921637
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Irreversible inhibition of 20S proteasome
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Highlights of marine invertebrate-derived biosynthetic products: their biomedical potential and possible production by microbial associants.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.10 | 8.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL371405 | MARIZOMIB | 3.0 | 1 | 8.89 |
| CHEMBL381627 | OMURALIDE | — | 1 | 7.31 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL371405 | MARIZOMIB | IC50 | = | 1.3 | nM | 8.89 |
| CHEMBL381627 | OMURALIDE | IC50 | = | 49.0 | nM | 7.31 |