Assay Detail
Binding
CHEMBL1925809
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Escherichia coli DNA topoisomerase 4-mediated relaxation of supercoiled pBR322 DNA
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Escherichia coli |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Ungeremine effectively targets mammalian as well as bacterial type I and type II topoisomerases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.14 | 5.14 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL479291 | UNGEREMINE | — | 1 | 5.14 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL479291 | UNGEREMINE | IC50 | = | 7300.0 | nM | 5.14 |