Assay Detail
Functional
CHEMBL1930614
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Cytotoxicity against human A549 cells after 3 days by SRB assay
12
Total Activities
12
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A549 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Bis-chalcone analogues as potent NO production inhibitors and as cytotoxic agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 12 | 5.07 | 5.39 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1928921 | — | — | 1 | 5.39 |
| CHEMBL1928924 | — | — | 1 | 5.36 |
| CHEMBL1928923 | — | — | 1 | 5.06 |
| CHEMBL1928925 | — | — | 1 | 5.04 |
| CHEMBL1929082 | — | — | 1 | 4.87 |
| CHEMBL1929083 | — | — | 1 | 4.71 |
| CHEMBL1928926 | — | — | 1 | - |
| CHEMBL1928928 | — | — | 1 | - |
| CHEMBL1926708 | — | — | 1 | - |
| CHEMBL1928929 | — | — | 1 | - |
| CHEMBL1929084 | — | — | 1 | - |
| CHEMBL1929085 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1928921 | — | EC50 | = | 4080.0 | nM | 5.39 |
| CHEMBL1928924 | — | EC50 | = | 4380.0 | nM | 5.36 |
| CHEMBL1928923 | — | EC50 | = | 8760.0 | nM | 5.06 |
| CHEMBL1928925 | — | EC50 | = | 9140.0 | nM | 5.04 |
| CHEMBL1929082 | — | EC50 | = | 13660.0 | nM | 4.87 |
| CHEMBL1929083 | — | EC50 | = | 19380.0 | nM | 4.71 |
| CHEMBL1928926 | — | EC50 | - | — | - | |
| CHEMBL1928928 | — | EC50 | - | — | - | |
| CHEMBL1926708 | — | EC50 | - | — | - | |
| CHEMBL1928929 | — | EC50 | - | — | - | |
| CHEMBL1929084 | — | EC50 | - | — | - | |
| CHEMBL1929085 | — | EC50 | - | — | - |