Assay Detail
ADMET
CHEMBL1932151
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Cytotoxicity against african green monkey Vero cells by green fluorescent protein microplate assay
11
Total Activities
11
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Chlorocebus sabaeus |
| Cell Type | Vero |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Lanostane and hopane triterpenes from the entomopathogenic fungus Hypocrella sp. BCC 14524.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Activity | 7 | - | - |
| IC50 | 4 | 4.69 | 5.01 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL123 | ELLIPTECINE | — | 1 | 5.01 |
| CHEMBL1928582 | — | — | 1 | 4.89 |
| CHEMBL1928579 | HYPOCRELLOL D | — | 1 | 4.52 |
| CHEMBL1928581 | — | — | 1 | 4.33 |
| CHEMBL1928577 | HYPOCRELLOL A | — | 1 | - |
| CHEMBL1928578 | HYPOCRELLOL B | — | 1 | - |
| CHEMBL1928576 | — | — | 1 | - |
| CHEMBL1928580 | — | — | 1 | - |
| CHEMBL1928583 | — | — | 1 | - |
| CHEMBL1928584 | — | — | 1 | - |
| CHEMBL1928585 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL123 | ELLIPTECINE | IC50 | = | 9800.0 | nM | 5.01 |
| CHEMBL1928582 | — | IC50 | = | 13000.0 | nM | 4.89 |
| CHEMBL1928579 | HYPOCRELLOL D | IC50 | = | 30000.0 | nM | 4.52 |
| CHEMBL1928581 | — | IC50 | = | 47000.0 | nM | 4.33 |
| CHEMBL1928577 | HYPOCRELLOL A | Activity | - | — | - | |
| CHEMBL1928578 | HYPOCRELLOL B | Activity | - | — | - | |
| CHEMBL1928576 | — | Activity | - | — | - | |
| CHEMBL1928580 | — | Activity | - | — | - | |
| CHEMBL1928583 | — | Activity | - | — | - | |
| CHEMBL1928584 | — | Activity | - | — | - | |
| CHEMBL1928585 | — | Activity | - | — | - |