Assay Detail
Binding
CHEMBL1936264
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Inhibition of Clostridium botulinum BoNT/A light chain after 40 mins by HPLC assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Clostridium botulinum |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Botulinum neurotoxin type A (CHEMBL5192) ↗| Type | SINGLE PROTEIN |
| Organism | Clostridium botulinum |
Publication
Time-dependent botulinum neurotoxin serotype A metalloprotease inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.77 | 5.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1933865 | — | — | 1 | 5.00 |
| CHEMBL1933882 | — | — | 1 | 4.54 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1933865 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL1933882 | — | IC50 | = | 29000.0 | nM | 4.54 |