Assay Detail
Binding
CHEMBL1936360
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Inhibition of p53/HDM2 interaction
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Hoiamide D, a marine cyanobacteria-derived inhibitor of p53/MDM2 interaction.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.94 | 5.34 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1935082 | — | — | 1 | 5.34 |
| CHEMBL276809 | SEMPERVIRINE | — | 1 | 4.53 |
| CHEMBL199341 | HEXYLITACONIC ACID | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1935082 | — | IC50 | = | 4600.0 | nM | 5.34 |
| CHEMBL276809 | SEMPERVIRINE | IC50 | = | 29400.0 | nM | 4.53 |
| CHEMBL199341 | HEXYLITACONIC ACID | IC50 | = | 230000.0 | nM | - |