Assay Detail
Binding
CHEMBL1936792
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Inhibition of IDO1 by magnetic circular dichroism spectroscopic analysis
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Novel indoleamine 2,3-dioxygenase-1 inhibitors from a multistep in silico screen.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.96 | 7.07 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL579014 | — | — | 1 | 7.07 |
| CHEMBL585186 | — | — | 1 | 6.00 |
| CHEMBL584992 | — | — | 1 | 5.85 |
| CHEMBL574139 | — | — | 1 | 5.68 |
| CHEMBL573686 | — | — | 1 | 5.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL579014 | — | IC50 | = | 86.0 | nM | 7.07 |
| CHEMBL585186 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL584992 | — | IC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL574139 | — | IC50 | = | 2100.0 | nM | 5.68 |
| CHEMBL573686 | — | IC50 | = | 6000.0 | nM | 5.22 |