Assay Detail
Functional
CHEMBL1937036
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Anticancer activity against human Hs578T cells after 96 hrs by SRB assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Hs-578T |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis, anticancer activity and pharmacokinetic analysis of 1-[(substituted 2-alkoxyquinoxalin-3-yl)aminocarbonyl]-4-(hetero)arylpiperazine derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 6.96 | 7.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1934205 | — | — | 1 | 7.82 |
| CHEMBL1934203 | — | — | 1 | 7.70 |
| CHEMBL1934204 | — | — | 1 | 7.32 |
| CHEMBL1934202 | — | — | 1 | 6.80 |
| CHEMBL1934199 | — | — | 1 | 6.50 |
| CHEMBL1934200 | — | — | 1 | 6.31 |
| CHEMBL1934201 | — | — | 1 | 6.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1934205 | — | IC50 | = | 15.0 | nM | 7.82 |
| CHEMBL1934203 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL1934204 | — | IC50 | = | 48.0 | nM | 7.32 |
| CHEMBL1934202 | — | IC50 | = | 160.0 | nM | 6.80 |
| CHEMBL1934199 | — | IC50 | = | 320.0 | nM | 6.50 |
| CHEMBL1934200 | — | IC50 | = | 490.0 | nM | 6.31 |
| CHEMBL1934201 | — | IC50 | = | 500.0 | nM | 6.30 |