Assay Detail

CHEMBL1937762

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional

Agonist activity at hamster PPARalpha

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

Open DB target context

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Unchecked (CHEMBL612545) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Cricetinae
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Discovery of cyclic amine-substituted benzoic acids as PPARα agonists.

Nomura M, Yumoto K, Shinozaki T, Isogai S, Takano Y, Murakami K.
Bioorg Med Chem Lett (2012) 22 : 334 -338
PubMed 22133631 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
EC50	1	6.21	6.21

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL1934476	—	—	1	6.21

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL1934476	—	EC50	=	610.0	nM	6.21