Assay Detail
Binding
CHEMBL1941202
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human MMP13-mediated degradation of bovine nasal cartilage after 2 hrs by ELISA in the presence of 10% human serum
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Tissue | Nasal cartilage |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Fragment-based discovery of indole inhibitors of matrix metalloproteinase-13.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.51 | 7.51 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1939876 | BI 4394 | — | 1 | 7.51 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1939876 | BI 4394 | IC50 | = | 31.0 | nM | 7.51 |