Assay Detail
Functional
CHEMBL1953409
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human PC3 cells after 24 hrs by WST-1 assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | PC-3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Novel synthesis and biological evaluation of enigmols as therapeutic agents for treating prostate cancer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.86 | 5.01 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1951763 | — | — | 1 | 5.01 |
| CHEMBL1951762 | — | — | 1 | 4.99 |
| CHEMBL1951761 | ENIGMOL | — | 1 | 4.99 |
| CHEMBL1951765 | — | — | 1 | 4.98 |
| CHEMBL1951764 | — | — | 1 | 4.31 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1951763 | — | IC50 | = | 9700.0 | nM | 5.01 |
| CHEMBL1951762 | — | IC50 | = | 10200.0 | nM | 4.99 |
| CHEMBL1951761 | ENIGMOL | IC50 | = | 10300.0 | nM | 4.99 |
| CHEMBL1951765 | — | IC50 | = | 10500.0 | nM | 4.98 |
| CHEMBL1951764 | — | IC50 | = | 49300.0 | nM | 4.31 |