Assay Detail
ADMET
CHEMBL1955241
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Cytotoxicity against african green monkey Vero cells after 48 hrs by neutral red assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Chlorocebus sabaeus |
| Cell Type | Vero |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and antikinetoplastid activity of a series of N,N'-substituted diamines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.31 | 5.57 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1950476 | — | — | 1 | 5.57 |
| CHEMBL1950478 | — | — | 1 | 5.57 |
| CHEMBL280180 | — | — | 1 | 5.23 |
| CHEMBL1950466 | — | — | 1 | 5.22 |
| CHEMBL1950475 | — | — | 1 | 5.18 |
| CHEMBL1950463 | — | — | 1 | 5.08 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1950476 | — | IC50 | = | 2700.0 | nM | 5.57 |
| CHEMBL1950478 | — | IC50 | = | 2700.0 | nM | 5.57 |
| CHEMBL280180 | — | IC50 | = | 5830.0 | nM | 5.23 |
| CHEMBL1950466 | — | IC50 | = | 6000.0 | nM | 5.22 |
| CHEMBL1950475 | — | IC50 | = | 6650.0 | nM | 5.18 |
| CHEMBL1950463 | — | IC50 | = | 8320.0 | nM | 5.08 |