Assay Detail
Functional
CHEMBL1958652
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Cytotoxicity against human BGC823 cells by MTT assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | BGC-823 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and antitumor activity of 5,6-dihydro-17-hydroxy icogenin analogs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.48 | 5.97 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL507001 | DIOSCIN | — | 1 | 5.97 |
| CHEMBL1958312 | — | — | 1 | 5.37 |
| CHEMBL1958313 | — | — | 1 | 5.10 |
| CHEMBL1958310 | — | — | 1 | - |
| CHEMBL1958311 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL507001 | DIOSCIN | IC50 | = | 1080.0 | nM | 5.97 |
| CHEMBL1958312 | — | IC50 | = | 4290.0 | nM | 5.37 |
| CHEMBL1958313 | — | IC50 | = | 7970.0 | nM | 5.10 |
| CHEMBL1958310 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL1958311 | — | IC50 | > | 10000.0 | nM | - |