Assay Detail
Binding
CHEMBL1959239
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Inhibition of ribonuclease H activity of Human immunodeficiency virus 1 reverse transcriptase Tyr181Cys mutant
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Human immunodeficiency virus 1 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Identification of HIV-1 reverse transcriptase dual inhibitors by a combined shape-, 2D-fingerprint- and pharmacophore-based virtual screening approach.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.19 | 5.19 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1958265 | — | — | 1 | 5.19 |
| CHEMBL223228 | EFAVIRENZ | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1958265 | — | IC50 | = | 6500.0 | nM | 5.19 |
| CHEMBL223228 | EFAVIRENZ | IC50 | - | — | - |