Assay Detail
Binding
CHEMBL1960794
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of CDK2
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Novel Rho kinase inhibitors with anti-inflammatory and vasodilatory activities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.31 | 5.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL220241 | GSK-269962A | — | 1 | 5.46 |
| CHEMBL1956071 | — | — | 1 | 5.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL220241 | GSK-269962A | IC50 | = | 3500.0 | nM | 5.46 |
| CHEMBL1956071 | — | IC50 | = | 7000.0 | nM | 5.16 |