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Assay Detail

CHEMBL1961267

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of rat liver casein kinase-2 preincubated for 5 mins prior ATP addition measured after 40 mins
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Indeno[1,2-b]indole derivatives as a novel class of potent human protein kinase CK2 inhibitors.
Hundsdörfer C, Hemmerling HJ, Götz C, Totzke F, Bednarski P, Le Borgne M, Jose J.
Bioorg Med Chem (2012) 20 : 2282 -2289
PubMed 22377675 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.05 6.05

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL289277 EMODIN 1 6.05

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL289277 EMODIN IC50 = 890.0 nM 6.05