Assay Detail
Functional
CHEMBL1963916
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PUBCHEM_BIOASSAY: Dose response confirmation of uHTS hits for small molecule modulators of myocardial damage - Set 2. (Class of assay: confirmatory)
620
Total Activities
620
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Tissue | Myocardium |
| Category | confirmatory |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
PubChem BioAssay data set
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 620 | 5.21 | 6.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1731294 | — | — | 1 | 6.48 |
| CHEMBL1408688 | — | — | 1 | 6.46 |
| CHEMBL1555363 | — | — | 1 | 6.42 |
| CHEMBL1598940 | — | — | 1 | 6.37 |
| CHEMBL1978228 | — | — | 1 | 6.29 |
| CHEMBL56897 | — | — | 1 | 6.21 |
| CHEMBL1708119 | — | — | 1 | 6.17 |
| CHEMBL1702908 | — | — | 1 | 6.14 |
| CHEMBL1474526 | — | — | 1 | 6.13 |
| CHEMBL1577620 | — | — | 1 | 6.12 |
| CHEMBL1415890 | — | — | 1 | 6.09 |
| CHEMBL1324195 | — | — | 1 | 6.03 |
| CHEMBL1346278 | — | — | 1 | 6.00 |
| CHEMBL1487964 | — | — | 1 | 5.97 |
| CHEMBL1395840 | — | — | 1 | 5.97 |
| CHEMBL1733950 | — | — | 1 | 5.96 |
| CHEMBL1731522 | — | — | 1 | 5.96 |
| CHEMBL1975458 | — | — | 1 | 5.96 |
| CHEMBL1374250 | — | — | 1 | 5.94 |
| CHEMBL1550273 | — | — | 1 | 5.92 |
| CHEMBL1726305 | — | — | 1 | 5.91 |
| CHEMBL1311274 | — | — | 1 | 5.91 |
| CHEMBL1545864 | — | — | 1 | 5.90 |
| CHEMBL1506609 | — | — | 1 | 5.90 |
| CHEMBL1352043 | — | — | 1 | 5.89 |
| CHEMBL1599015 | — | — | 1 | 5.88 |
| CHEMBL1703524 | — | — | 1 | 5.87 |
| CHEMBL1352434 | — | — | 1 | 5.87 |
| CHEMBL1399390 | — | — | 1 | 5.86 |
| CHEMBL1730650 | — | — | 1 | 5.86 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1731294 | — | IC50 | = | 330.0 | nM | 6.48 |
| CHEMBL1408688 | — | IC50 | = | 350.0 | nM | 6.46 |
| CHEMBL1555363 | — | IC50 | = | 380.0 | nM | 6.42 |
| CHEMBL1598940 | — | IC50 | = | 430.0 | nM | 6.37 |
| CHEMBL1978228 | — | IC50 | = | 510.0 | nM | 6.29 |
| CHEMBL56897 | — | IC50 | = | 611.0 | nM | 6.21 |
| CHEMBL1708119 | — | IC50 | = | 668.0 | nM | 6.17 |
| CHEMBL1702908 | — | IC50 | = | 729.0 | nM | 6.14 |
| CHEMBL1474526 | — | IC50 | = | 747.0 | nM | 6.13 |
| CHEMBL1577620 | — | IC50 | = | 750.0 | nM | 6.12 |
| CHEMBL1415890 | — | IC50 | = | 815.0 | nM | 6.09 |
| CHEMBL1324195 | — | IC50 | = | 940.0 | nM | 6.03 |
| CHEMBL1346278 | — | IC50 | = | 998.0 | nM | 6.00 |
| CHEMBL1487964 | — | IC50 | = | 1070.0 | nM | 5.97 |
| CHEMBL1395840 | — | IC50 | = | 1080.0 | nM | 5.97 |
| CHEMBL1733950 | — | IC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL1975458 | — | IC50 | = | 1090.0 | nM | 5.96 |
| CHEMBL1731522 | — | IC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL1374250 | — | IC50 | = | 1150.0 | nM | 5.94 |
| CHEMBL1550273 | — | IC50 | = | 1210.0 | nM | 5.92 |
| CHEMBL1726305 | — | IC50 | = | 1220.0 | nM | 5.91 |
| CHEMBL1311274 | — | IC50 | = | 1220.0 | nM | 5.91 |
| CHEMBL1506609 | — | IC50 | = | 1260.0 | nM | 5.90 |
| CHEMBL1545864 | — | IC50 | = | 1250.0 | nM | 5.90 |
| CHEMBL1352043 | — | IC50 | = | 1300.0 | nM | 5.89 |
| CHEMBL1599015 | — | IC50 | = | 1320.0 | nM | 5.88 |
| CHEMBL1703524 | — | IC50 | = | 1360.0 | nM | 5.87 |
| CHEMBL1352434 | — | IC50 | = | 1340.0 | nM | 5.87 |
| CHEMBL1399390 | — | IC50 | = | 1380.0 | nM | 5.86 |
| CHEMBL1730650 | — | IC50 | = | 1390.0 | nM | 5.86 |
| CHEMBL590457 | — | IC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL1699659 | — | IC50 | = | 1480.0 | nM | 5.83 |
| CHEMBL1497909 | — | IC50 | = | 1490.0 | nM | 5.83 |
| CHEMBL1722488 | — | IC50 | = | 1510.0 | nM | 5.82 |
| CHEMBL1881477 | — | IC50 | = | 1560.0 | nM | 5.81 |
| CHEMBL1545153 | — | IC50 | = | 1580.0 | nM | 5.80 |
| CHEMBL1723414 | — | IC50 | = | 1570.0 | nM | 5.80 |
| CHEMBL1393529 | — | IC50 | = | 1580.0 | nM | 5.80 |
| CHEMBL1373281 | — | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL1966657 | — | IC50 | = | 1610.0 | nM | 5.79 |
| CHEMBL1369130 | — | IC50 | = | 1660.0 | nM | 5.78 |
| CHEMBL1468363 | — | IC50 | = | 1680.0 | nM | 5.78 |
| CHEMBL1707466 | — | IC50 | = | 1710.0 | nM | 5.77 |
| CHEMBL1503607 | — | IC50 | = | 1710.0 | nM | 5.77 |
| CHEMBL1993978 | — | IC50 | = | 1780.0 | nM | 5.75 |
| CHEMBL1346308 | — | IC50 | = | 1800.0 | nM | 5.75 |
| CHEMBL1540513 | — | IC50 | = | 1780.0 | nM | 5.75 |
| CHEMBL1558819 | — | IC50 | = | 1960.0 | nM | 5.71 |
| CHEMBL1491564 | — | IC50 | = | 1980.0 | nM | 5.70 |
| CHEMBL1495663 | — | IC50 | = | 1980.0 | nM | 5.70 |