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Assay Detail

CHEMBL2013696

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Non-competitive inhibition of calf DNA polymerase alpha using ploy(dA)/oligo(dT)18 as substrate by Dixon plot analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Bos taurus
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Pinophilins A and B, inhibitors of mammalian A-, B-, and Y-family DNA polymerases and human cancer cell proliferation.
Myobatake Y, Takeuchi T, Kuramochi K, Kuriyama I, Ishido T, Hirano K, Sugawara F, Yoshida H, Mizushina Y.
J Nat Prod (2012) 75 : 135 -141
PubMed 22264170 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 4.86 4.86

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2011646 PINOPHILIN A 1 4.86

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2011646 PINOPHILIN A Ki = 13800.0 nM 4.86